Ferritin heavy chain fth
WebFerritin Heavy Chain contains a number of potential phosphorylation sites (SwissProt data) which may explain it running at a slightly higher than predicted molecular weight (24 kDa). Immunohistochemistry … WebFerritin heavy chain (FTH1) is a 21-kDa subunit of the ferritin complex, known for its role in iron metabolism. FTH1 contributes to an anti-tumor response in breast cancer patients. Human piRNA (piR-FTH1) has a complementary sequence in the ferritin heavy chain 1 …
Ferritin heavy chain fth
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Webferritin heavy chain Antibody (B-12) is an IgG 2a κ mouse monoclonal ferritin heavy chain antibody (also designated ferritin heavy chain 1 antibody, or FHC antibody) suitable for the detection of the ferritin heavy chain protein of mouse, rat and human origin by WB, IP, IF and ELISA. ferritin heavy chain Antibody (B-12) is available as both the … WebIn this study, we have demonstrated that the ferritin heavy chain (FTH) could be degraded via chaperone-mediated autophagy (CMA) in ER stress/p38-dependent pathway. In HeLa cells, inducing the ER stress activated CMA, therefore facilitated the degradation of FTH, and increased the content of Fe2+.
WebDec 29, 2024 · Ferritin heavy chain (FTH) is a major iron storing nanocage to store redox-inactive iron, and harbors ferroxidase activity to prevent the iron-mediated … Webferritin heavy chain Antibody (B-12) is a mouse monoclonal IgG 2a κ ferritin heavy chain antibody, cited in 58 publications, provided at 200 µg/ml. raised against amino acids 131 …
WebNov 3, 2014 · The iron storage protein ferritin is a complex of 24 ferritin light chain (FTL; 134790) and ferritin heavy chain (FTH1) subunits in ratios that vary in different cell …
WebSep 1, 2024 · FTH and FTL built protein complexes composed of 24 subunits. FTH as well as FTMT carry a ferroxidase activity, which allows storage of ferric hydroxides (Fe3+) instead of reactive ferrous iron (Fe 2+) [ 10 ]. Iron loading of FTH is mediated by poly (rC)-binding protein 1 (PCBP1) [ 11]. 6孔板面积和12孔板面积WebFerritin H subunit; FTH; FTHL6; Gene Name FTH1 Organism Humans Amino acid sequence ... Harford JB, Klausner RD: Cloning, characterization, expression, and … tau610Web本发明提供一种磁共振可视化且能用于免疫治疗胶质瘤的间充质干细胞制剂，通过对mscs进行cxcl10(免疫治疗基因)、nrf2(抗凋亡基因)及fth(mri报告基因)联合修饰，获得cxcl10分泌上调，同具有抗凋亡能力的mri可视化mscs，上调抗凋亡基因增强mscs的长期存活率，将其作为持续分泌cxcl10的“细胞工厂”，增强 ... 6太WebFeb 12, 2016 · Ferritin light chain (FTL), a key protein in iron metabolism, is associated with the survival of glioblastoma multiforme (GBM) patients; however, the molecular mechanisms underlying this association remain largely unclear. Therefore, in the present study, we investigated the role of FTL in the pathogenesis of GBM. tau-5抗体WebMechanisms controlling iron-loading of transferrin and or lactotransferrin may impact ferroptosis. On the other hand, cells must buffer their intracellular iron by using cytosolic iron storage proteins such as NCOA4 and ferritins. Mitochondrial ferritin (mtFt) and H-chain ferritin (FTH) are the most known iron storage proteins in the brain. 6塔WebFeb 26, 2024 · Ferritin is composed by 24 subunits of acidic/heavy (H) (FTH) and basic/light (L) (FTL) chains. It acts as intracellular iron nanocage that accumulates large amounts of iron in its cavity (up to 4,000 per molecule) to prevent oxidative stress, and to release it in iron deprivation conditions ( 29 ). 6 后缀表达式计算 100 分WebThe ferritin heavy chain (FtH) has ferroxidase activity that is required for iron incorporation and limiting toxicity. The purpose of this study was to investigate the role of FtH in acute kidney injury (AKI) and renal iron handling by using proximal tubule-specific FtH-knockout mice (FtH (PT-/-) mice). 6場計画