2024 Erythropoietin-producing hepatoma

Erythropoietin-producing hepatoma

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August undefined, 2024

WebThe erythropoietin-producing hepatoma (Eph) receptor tyrosine kinase A2 (EphA2) and its ligand, ephrinA1, play a pivotal role in inflammation and tissue injury by modulating the … WebDec 31, 2024 · Eph (erythropoietin-producing hepatoma) is a big family of receptor tyrosine kinases and plays key roles in physiological and pathological processes in …

The regulated expression of erythropoietin by two human …

WebEph (erythropoietin-producing hepatoma) receptors and Ephrin ligands constitute the largest subfamily of receptor tyrosine kinase (RTK), which were first discovered in tumors. … WebMay 30, 2024 · e15660 Background: Erythropoietin (Epo) is a glycoprotein that stimulates cell proliferation and angiogenesis. Both, hypoxia and anemia are triggering factors that induce Epo overproduction. Although, previous studies reported that Epo induces angiogenesis in hepatocellular cancer (HCC), the relationship between Epo and HCC … alli levine 9news

Erythropoietin: An Historical Overview of Physiology

WebAug 15, 2013 · As early as the 19th century, scientists recognized the correlation between low atmospheric oxygen pressure and elevated red blood cell numbers in humans and animals. 1 Several decades later, it became evident that low oxygen does not directly act on hematopoietic cells but induces the production of a soluble factor called erythropoietin … WebDec 12, 2010 · INTRODUCTION. Erythropoietin-producing hepatoma (EPH) amplified sequence is an acronym for erythropoietin-producing hepatocellular carcinoma[] from which the first member of the EPH family was isolated.The involvement of one gene in this family in human gastric cancer was reported in 1994[] prior to the designation of this … al lil abner

Eph receptors: the bridge linking host and virus SpringerLink

Eph receptors: the bridge linking host and virus - PubMed

WebBackground: Signaling induced by binding of erythropoietin-producing hepatoma-amplified sequence (EPH) receptors to their cell-surface ephrin ligands is implicated in … WebThe erythropoietin-producing hepatoma (Eph) family of receptor tyrosine kinases as well as the ephrins, ligands of their membrane bound, have been found to play important roles in regulating cell adhesion and migration during cancer development. 10 Roles of EPHB2 and EPHB4 in colon cancer have been extensively studied, 11 for example, EPHB2 ... alliliciWebPatients with hepatocellular carcinoma sometimes have erythrocytosis and high plasma erythropoietin levels. However, previous studies have not revealed direct evidence that … allilico

"WebTwo cases are reported in which an erythrocytosis was seen in patients subsequently found to have primary carcinoma of the liver. In one of these, raised levels of erythropoietin were demonstrated in plasma. Hepatoma should be considered in the differential diagnosis of erythrocytosis where hypoxia is not present. " - Erythropoietin-producing hepatoma

Erythropoietin-producing hepatoma

The regulated expression of erythropoietin by two human

WebJan 1, 2009 · Further analysis of these sequences was facilitated by the use of erythropoietin producing hepatoma cell lines that demonstrated the same dynamic hypoxic response as the whole organism, and could be studied in tissue culture. Using these cell lines, reporter assays, in which 3′ erythropoietin flanking sequences were fused to … WebTwo cases are reported in which an erythrocytosis was seen in patients subsequently found to have primary carcinoma of the liver. In one of these, raised levels of erythropoietin …

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WebSep 4, 2007 · The erythropoietin-producing hepatoma-amplified sequence (Eph) receptors are a large family of receptor tyrosine kinases comprising eight EphA and six … WebApr 27, 2024 · Erythropoietin-producing hepatocellular carcinoma receptor (Eph) and their cell-associated ephrin ligands are associated with neoangiogenesis and invasive tumor progression, and are progressively being focused as new therapeutic targets in clinical trials . Ephs and ephrins are abundantly found in multiple types of tumors, where their …

WebA case of erythrocytosis caused by a hepatocellular carcinoma (HCC) that produced erythropoietin (Epo) is described. A 64-year-old man, with a huge HCC tumor in the … WebThe erythropoietin-producing hepatocellular carcinoma (Eph) receptor tyrosine kinase family plays important roles in developmental processes, adult tissue homeostasis, and …

WebMay 1, 1995 · Microelectrode measurements of pericellular P% in erythropoietin-producing human hepatoma cell cultures. Am. J. Physiol. 265: C1266- C1270. Yamada, T., J.J. Yang, N.V. Ricchiuti and M.W. Seraydarian (1985). Oxygen consumption of mammalian myocardial cells in culture: measurements in beating cells attached to the substrate of … WebDec 1, 2000 · A case of erythrocytosis caused by a hepatocellular carcinoma (HCC) that produced erythropoietin (Epo) is described. A 64-year-old man, with a huge HCC tumor in the right lobe of the liver, showed ...

WebJan 1, 2024 · The important role of the kidney in erythropoietin production became apparent when Leon Jacobson (1911–92) ... (at least as manifest in the erythropoietin-producing hepatoma cells) and the erythropoietin gene locus. Unexpectedly, however, transfection studies of the 3′ erythropoietin enhancer also demonstrated oxygen …

WebDec 20, 2024 · Hepatocellular carcinoma (HCC) is a primary tumor of the liver that usually develops in the setting of chronic liver disease, particularly in patients with cirr ... allilicaWebApr 12, 2024 · Among these pathways, ephrin/erythropoietin‐producing hepatoma receptor B4 (EPH receptor B4; EphB4) may be particularly important for the development of endometriosis, because EphB4 is overexpressed in ectopic endometrium when compared to eutopic endometrium of women with endometriosis (Yerlikaya et al., 2016). all illegal agreements are voidWebFeb 5, 2024 · To this end, they focused their study on the erythropoietin-producing hepatoma receptor tyrosine kinase A2 (EphA2), a membrane protein that is strongly expressed in cancer cells. The findings revealed that the presence or absence of ligand-bound receptors (EphrinA-EphA2) influenced cancer progression via interactions with … all illinois area codesWebSep 1, 1998 · The plasma level of erythropoietin (Epo) in anemic patients suffering from inflammation is often low in relation to the blood hemoglobin concentration. Various proinflammatory cytokines have been ... all i like is pizzaWebApr 12, 2024 · Among these pathways, ephrin/erythropoietin‐producing hepatoma receptor B4 (EPH receptor B4; EphB4) may be particularly important for the development … all i lettersWebwhere erythropoietin is made under physiologic conditions. PHYSIOLOGY OF THE CRITMETER Renal tissue oxygen pressure most likely acts as the common signal integrating the relative amounts of the plasma volume and the red blood cell mass (Fig 2).13 Tissue culture studies of the erythropoietin-producing hepatoma 3B cells show all ilesWebDec 20, 2024 · Hepatocellular carcinoma (HCC) is a primary tumor of the liver that usually develops in the setting of chronic liver disease, particularly in patients with cirr ... Sakisaka S, Watanabe M, Tateishi H, et al. Erythropoietin production in hepatocellular carcinoma cells associated with polycythemia: immunohistochemical evidence. Hepatology 1993 ... all illinois colleges